PDB 4uvl

PDB Information

PDB4UVL
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI BL21(DE3)
Gene SourceHOMO SAPIENS
Primary Citation
Exploration of the Nicotinamide-Binding Site of the Tankyrases, Identifying 3-Arylisoquinolin-1-Ones as Potent and Selective Inhibitors in Vitro.
Paine, H.A., Nathubhai, A., Woon, E.C.Y., Sunderland, P.T., Wood, P.J., Mahon, M.F., Lloyd, M.D., Thompson, A.S., Haikarainen, T., Narwal, M., Lehtio, L., Threadgill, M.D.
Bioorg.Med.Chem.
HeaderTransferase
Released2014-08-07
Resolution2.000
CATH Insert Date16 Aug, 2015

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 17 Aug, 2015 Chopped
C 17 Aug, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4uvlA00 24 Aug, 2015 3.90.228.10 Assigned
4uvlC00 24 Aug, 2015 3.90.228.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9H2K2 TNKS2_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2 TNKS2_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-2
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