PDB 4uv8

PDB Information

PDB4UV8
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI BL21
Gene SourceHOMO SAPIENS
Primary Citation
Synthesis, Biological Activity and Mechanistic Insights of 1-Substituted Cyclopropylamine Derivatives: A Novel Class of Irreversible Inhibitors of Histone Demethylase Kdm1A.
Vianello, P., Botrugno, O.A., Cappa, A., Ciossani, G., Dessanti, P., Mai, A., Mattevi, A., Meroni, G., Minucci, S., Thaler, F., Tortorici, M., Trifiro, P., Valente, S., Villa, M., Varasi, M., Mercurio, C.
Eur.J.Med.Chem.
HeaderTranscription
Released2014-08-05
Resolution2.800
CATH Insert Date14 Sep, 2014

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 15 Sep, 2014 Chopped
B 15 Sep, 2014 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4uv8A01 16 Sep, 2014 1.10.10.10 Assigned
4uv8A02 16 Sep, 2014 Holding pen
4uv8A03 16 Sep, 2014 1.10.287.80 Assigned
4uv8B00 16 Sep, 2014 1.20.58.1880 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O60341 KDM1A_HUMAN Homo sapiens Lysine-specific histone demethylase 1A
Q9UKL0 RCOR1_HUMAN Homo sapiens REST corepressor 1
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