PDB 4umx
PDB Information
PDB | 4UMX |
Method | X-RAY DIFFRACTION |
Host Organism | ESCHERICHIA COLI |
Gene Source | HOMO SAPIENS |
Primary Citation | Selective Inhibition of Mutant Isocitrate Dehydrogenase 1 (Idh1) Via Disruption of a Metal Binding Network by an Allosteric Small Molecule.
J.Biol.Chem.
|
Header | Oxidoreductase |
Released | 2014-05-22 |
Resolution | 1.880 |
CATH Insert Date | 30 Nov, 2014 |
PDB Images (5)
PDB Prints
PDB Chains (2)
Chain ID | Date inserted into CATH | CATH Status |
---|---|---|
A | 01 Dec, 2014 | Chopped |
B | 01 Dec, 2014 | Chopped |
CATH Domains (2)
Domain ID | Date inserted into CATH | Superfamily | CATH Status |
---|---|---|---|
4umxA00 | 03 Dec, 2014 | 3.40.718.10 | Assigned |
4umxB00 | 03 Dec, 2014 | 3.40.718.10 | Assigned |
UniProtKB Entries (2)
Accession | Gene ID | Taxon | Description |
---|---|---|---|
O75874 | IDHC_HUMAN | Homo sapiens | Isocitrate dehydrogenase [NADP] cytoplasmic |
O75874 | IDHC_HUMAN | Homo sapiens | Isocitrate dehydrogenase [NADP] cytoplasmic |