PDB 4ump

PDB Links
Overview

PDB Information

PDB	4UMP
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	HOMO SAPIENS
Primary Citation	Fragment-Based Discovery of Type I Inhibitors of Maternal Embryonic Leucine Zipper Kinase Johnson, C.N., Berdini, V., Beke, L., Bonnet, P., Brehmer, D., Coyle, J.E., Day, P.J., Frederickson, M., Freyne, E.J.E., Gilissen, R.A.H.J., Hamlett, C.C.F., Howard, S., Meerpoel, L., Mcmenamin, R., Patel, S., Rees, D.C., Sharff, A., Sommen, F., Wu, T., Linders, J.T.M. Acs Med.Chem.Lett.
Header	Transferase
Released	2014-05-20
Resolution	2.300
CATH Insert Date	19 Oct, 2014

PDB Images (9)

Image of CATH 4ump

4ump

PDB 4ump

Image of CATH 4umpA

4umpA

PDB Chain 4umpA

Image of CATH 4umpB

4umpB

PDB Chain 4umpB

Image of CATH 4umpC

4umpC

PDB Chain 4umpC

Image of CATH 4umpD

4umpD

PDB Chain 4umpD

Image of CATH 4umpA00

4umpA00

CATH Domain 4umpA00

Image of CATH 4umpB00

4umpB00

CATH Domain 4umpB00

Image of CATH 4umpC00

4umpC00

CATH Domain 4umpC00

Image of CATH 4umpD00

4umpD00

CATH Domain 4umpD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	20 Oct, 2014	Chopped
B	20 Oct, 2014	Chopped
C	20 Oct, 2014	Chopped
D	20 Oct, 2014	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4umpA00	21 Oct, 2014	1.10.510.10	Assigned
4umpB00	21 Oct, 2014	1.10.510.10	Assigned
4umpC00	21 Oct, 2014	1.10.510.10	Assigned
4umpD00	21 Oct, 2014	1.10.510.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q14680	MELK_HUMAN	Homo sapiens	Maternal embryonic leucine zipper kinase
Q14680	MELK_HUMAN	Homo sapiens	Maternal embryonic leucine zipper kinase
Q14680	MELK_HUMAN	Homo sapiens	Maternal embryonic leucine zipper kinase
Q14680	MELK_HUMAN	Homo sapiens	Maternal embryonic leucine zipper kinase