PDB 4u7z
PDB Information
PDB | 4U7Z |
Method | X-RAY DIFFRACTION |
Host Organism | Escherichia coli |
Gene Source | Homo sapiens |
Primary Citation | Structure based design of novel 6,5 heterobicyclic mitogen-activated protein kinase kinase (MEK) inhibitors leading to the discovery of imidazo[1,5-a] pyrazine G-479.
Bioorg.Med.Chem.Lett.
|
Header | Transferase/Transferase Inhibitor |
Released | 2014-07-31 |
Resolution | 2.810 |
CATH Insert Date | 05 Oct, 2014 |
PDB Images (4)
PDB Prints
PDB Chains (1)
Chain ID | Date inserted into CATH | CATH Status |
---|---|---|
A | 06 Oct, 2014 | Chopped |
CATH Domains (2)
Domain ID | Date inserted into CATH | Superfamily | CATH Status |
---|---|---|---|
4u7zA01 | 07 Oct, 2014 | 3.30.200.20 | Assigned |
4u7zA02 | 07 Oct, 2014 | 1.10.510.10 | Assigned |
UniProtKB Entries (1)
Accession | Gene ID | Taxon | Description |
---|---|---|---|
Q02750 | MP2K1_HUMAN | Homo sapiens | Dual specificity mitogen-activated protein kinase kinase 1 |