PDB Information

PDB4U6R
MethodX-RAY DIFFRACTION
Host OrganismTrichoplusia ni
Gene SourceHomo sapiens
Primary Citation
Unfolded Protein Response in Cancer: IRE1 alpha Inhibition by Selective Kinase Ligands Does Not Impair Tumor Cell Viability.
Harrington, P.E., Biswas, K., Malwitz, D., Tasker, A.S., Mohr, C., Andrews, K.L., Dellamaggiore, K., Kendall, R., Beckmann, H., Jaeckel, P., Materna-Reichelt, S., Allen, J.R., Lipford, J.R.
Acs Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2014-07-29
Resolution2.500
CATH Insert Date19 Oct, 2014

PDB Images (5)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 20 Oct, 2014 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4u6rA01 21 Oct, 2014 3.30.200.20 Assigned
4u6rA02 21 Oct, 2014 1.10.510.10 Assigned
4u6rA03 21 Oct, 2014 1.20.1440.180 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O75460 ERN1_HUMAN Homo sapiens Serine/threonine-protein kinase/endoribonuclease IRE1
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