PDB 4u6a

PDB Information

PDB4U6A
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design and discovery of 3-aryl-5-substituted-isoquinolin-1- ones as potent and selective tankyrase inhibitors
Elliot, R.J., Jarvis, A., Rajasekaran, M.B., Menon, M., Bowers, L., Boffey, R., Bayford, M., Firth-Clark, S., Beevers, R., Aquil, R., Kirton, S.B., Niculescu-Duvaz, D., Fish, L., Lopes, F., McLeary, R., Trindade, I., Vendrell, E., Munkonge, F., Porter, R., Perrior, T., Springer, C., Oliver, A.W., Pearl, L.H., Ashworth, A., Lord, C.J.
To be published
HeaderTransferase
Released2014-07-28
Resolution2.370
CATH Insert Date26 Jul, 2015

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 27 Jul, 2015 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4u6aA00 30 Jul, 2015 3.90.228.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O95271 TNKS1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-1
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