PDB Information

PDB4TYO
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-based design of novel human Pin1 inhibitors (III): Optimizing affinity beyond the phosphate recognition pocket.
Guo, C., Hou, X., Dong, L., Marakovits, J., Greasley, S., Dagostino, E., Ferre, R., Catherine Johnson, M., Humphries, P.S., Li, H., Paderes, G.D., Piraino, J., Kraynov, E., Murray, B.W.
Bioorg.Med.Chem.Lett.
HeaderIsomerase/Isomerase Inhibitor
Released2014-07-08
Resolution1.750
CATH Insert Date24 Aug, 2014

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 25 Aug, 2014 Chopped
B 25 Aug, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4tyoA00 29 Aug, 2014 3.10.50.40 Assigned
4tyoB00 29 Aug, 2014 3.10.50.40 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q13526 PIN1_HUMAN Homo sapiens Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Q13526 PIN1_HUMAN Homo sapiens Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1