PDB Information

PDB4TWW
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHuman SARS coronavirus
Primary Citation
Fused-ring structure of decahydroisoquinolin as a novel scaffold for SARS 3CL protease inhibitors
Shimamoto, Y., Hattori, Y., Kobayashi, K., Teruya, K., Sanjoh, A., Nakagawa, A., Yamashita, E., Akaji, K.
Bioorg.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2014-07-02
Resolution2.420
CATH Insert Date28 Jun, 2015

PDB Images (9)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4twwA01 15 Jul, 2015 2.40.10.10 Assigned
4twwA02 15 Jul, 2015 2.40.10.10 Assigned
4twwA03 15 Jul, 2015 1.10.1840.10 Assigned
4twwB01 15 Jul, 2015 2.40.10.10 Assigned
4twwB02 15 Jul, 2015 2.40.10.10 Assigned
4twwB03 15 Jul, 2015 1.10.1840.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P0C6U8 R1A_CVHSA Severe acute respiratory syndrome-related coronavirus Replicase polyprotein 1a
P0C6U8 R1A_CVHSA Severe acute respiratory syndrome-related coronavirus Replicase polyprotein 1a
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