PDB Information

PDB4TUY
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceRattus norvegicus
Primary Citation
A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs.
Prota, A.E., Bargsten, K., Diaz, J.F., Marsh, M., Cuevas, C., Liniger, M., Neuhaus, C., Andreu, J.M., Altmann, K.H., Steinmetz, M.O.
Proc.Natl.Acad.Sci.USA
HeaderCell Cycle
Released2014-06-25
Resolution2.100
CATH Insert Date07 Sep, 2014

PDB Images (23)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 08 Sep, 2014 Chopped
B 08 Sep, 2014 Chopped
C 08 Sep, 2014 Chopped
D 08 Sep, 2014 Chopped
E 08 Sep, 2014 Chopped
F 08 Sep, 2014 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
4tuyA01 10 Sep, 2014 3.40.50.1440 Assigned
4tuyA02 10 Sep, 2014 3.30.1330.20 Assigned
4tuyA03 10 Sep, 2014 1.10.287.600 Assigned
4tuyB01 10 Sep, 2014 3.40.50.1440 Assigned
4tuyB02 10 Sep, 2014 3.30.1330.20 Assigned
4tuyB03 10 Sep, 2014 1.10.287.600 Assigned
4tuyC01 10 Sep, 2014 3.40.50.1440 Assigned
4tuyC02 10 Sep, 2014 3.30.1330.20 Assigned
4tuyC03 10 Sep, 2014 1.10.287.600 Assigned
4tuyD01 10 Sep, 2014 3.40.50.1440 Assigned
4tuyD02 10 Sep, 2014 3.30.1330.20 Assigned
4tuyD03 10 Sep, 2014 1.10.287.600 Assigned
4tuyE01 10 Sep, 2014 6.10.280.30 Assigned
4tuyF01 10 Sep, 2014 3.40.50.11480 Assigned
4tuyF02 10 Sep, 2014 3.30.470.20 Assigned
4tuyF03 10 Sep, 2014 3.30.1490.20 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain
P81947 TBA1B_BOVIN Bos taurus Tubulin alpha-1B chain
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain
P81947 TBA1B_BOVIN Bos taurus Tubulin alpha-1B chain
E1BQ43 E1BQ43_CHICK Gallus gallus Uncharacterized protein
P63043 STMN4_RAT Rattus norvegicus Stathmin-4
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