PDB Information

PDB4TPT
MethodX-RAY DIFFRACTION
Host Organismunidentified baculovirus
Gene SourceHomo sapiens
Primary Citation
Discovery of a Type III Inhibitor of LIM Kinase 2 That Binds in a DFG-Out Conformation.
Goodwin, N.C., Cianchetta, G., Burgoon, H.A., Healy, J., Mabon, R., Strobel, E.D., Allen, J., Wang, S., Hamman, B.D., Rawlins, D.B.
Acs Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2014-06-09
Resolution2.600
CATH Insert Date09 Nov, 2014

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 10 Nov, 2014 Chopped
B 10 Nov, 2014 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4tptA01 13 Nov, 2014 3.30.200.20 Assigned
4tptA02 13 Nov, 2014 1.10.510.10 Assigned
4tptB01 12 Nov, 2014 3.30.200.20 Assigned
4tptB02 12 Nov, 2014 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P53671 LIMK2_HUMAN Homo sapiens LIM domain kinase 2
P53671 LIMK2_HUMAN Homo sapiens LIM domain kinase 2
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