PDB 4rj7

PDB Information

PDB4RJ7
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of Selective and Noncovalent Diaminopyrimidine-Based Inhibitors of Epidermal Growth Factor Receptor Containing the T790M Resistance Mutation.
Hanan, E.J., Eigenbrot, C., Bryan, M.C., Burdick, D.J., Chan, B.K., Chen, Y., Dotson, J., Heald, R.A., Jackson, P.S., La, H., Lainchbury, M.D., Malek, S., Purkey, H.E., Schaefer, G., Schmidt, S., Seward, E.M., Sideris, S., Tam, C., Wang, S., Yeap, S.K., Yen, I., Yin, J., Yu, C., Zilberleyb, I., Heffron, T.P.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2014-10-08
Resolution2.550
CATH Insert Date07 Dec, 2014

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 Dec, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4rj7A01 29 Dec, 2014 3.30.200.20 Assigned
4rj7A02 29 Dec, 2014 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor
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