PDB 4r6v

PDB Information

PDB4R6V
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors.
Tan, L., Wang, J., Tanizaki, J., Huang, Z., Aref, A.R., Rusan, M., Zhu, S.J., Zhang, Y., Ercan, D., Liao, R.G., Capelletti, M., Zhou, W., Hur, W., Kim, N., Sim, T., Gaudet, S., Barbie, D.A., Yeh, J.R., Yun, C.H., Hammerman, P.S., Mohammadi, M., Janne, P.A., Gray, N.S.
Proc.Natl.Acad.Sci.USA
HeaderTransferase/Transferase Inhibitor
Released2014-08-26
Resolution2.350
CATH Insert Date09 Nov, 2014

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 10 Nov, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4r6vA01 14 Nov, 2014 3.30.200.20 Assigned
4r6vA02 14 Nov, 2014 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P22455 FGFR4_HUMAN Homo sapiens Fibroblast growth factor receptor 4
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