PDB 4r5y

PDB Links
Overview

PDB Information

PDB	4R5Y
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli BL21(DE3)
Gene Source	Homo sapiens
Primary Citation	BGB-283, a Novel RAF Kinase and EGFR Inhibitor, Displays Potent Antitumor Activity in BRAF-Mutated Colorectal Cancers. Tang, Z., Yuan, X., Du, R., Cheung, S.H., Zhang, G., Wei, J., Zhao, Y., Feng, Y., Peng, H., Zhang, Y., Du, Y., Hu, X., Gong, W., Liu, Y., Gao, Y., Liu, Y., Hao, R., Li, S., Wang, S., Ji, J., Zhang, L., Li, S., Sutton, D., Wei, M., Zhou, C., Wang, L., Luo, L. Mol.Cancer Ther.
Header	Transferase/Transferase Inhibitor
Released	2014-08-22
Resolution	3.500
CATH Insert Date	10 Apr, 2016

PDB Images (7)

Image of CATH 4r5y

4r5y

PDB 4r5y

Image of CATH 4r5yA

4r5yA

PDB Chain 4r5yA

Image of CATH 4r5yB

4r5yB

PDB Chain 4r5yB

Image of CATH 4r5yA01

4r5yA01

CATH Domain 4r5yA01

Image of CATH 4r5yA02

4r5yA02

CATH Domain 4r5yA02

Image of CATH 4r5yB01

4r5yB01

CATH Domain 4r5yB01

Image of CATH 4r5yB02

4r5yB02

CATH Domain 4r5yB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	11 Apr, 2016	Chopped
B	11 Apr, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4r5yA01	28 Apr, 2016	3.30.200.20	Assigned
4r5yA02	28 Apr, 2016	1.10.510.10	Assigned
4r5yB01	28 Apr, 2016	3.30.200.20	Assigned
4r5yB02	28 Apr, 2016	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf