PDB 4r3o

PDB Links
Overview

PDB Information

PDB	4R3O
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Crystal Structure of the Human 20S Proteasome in Complex with Carfilzomib. Harshbarger, W., Miller, C., Diedrich, C., Sacchettini, J. Structure
Header	Hydrolase
Released	2014-08-16
Resolution	2.600
CATH Insert Date	28 Jun, 2015

PDB Images (57)

4r3o

PDB 4r3o

4r3o1

PDB Chain 4r3o1

4r3o2

PDB Chain 4r3o2

4r3oA

PDB Chain 4r3oA

4r3oB

PDB Chain 4r3oB

4r3oC

PDB Chain 4r3oC

4r3oD

PDB Chain 4r3oD

4r3oE

PDB Chain 4r3oE

4r3oF

PDB Chain 4r3oF

4r3oG

PDB Chain 4r3oG

4r3oH

PDB Chain 4r3oH

4r3oI

PDB Chain 4r3oI

4r3oJ

PDB Chain 4r3oJ

4r3oK

PDB Chain 4r3oK

4r3oL

PDB Chain 4r3oL

4r3oM

PDB Chain 4r3oM

4r3oN

PDB Chain 4r3oN

4r3oO

PDB Chain 4r3oO

4r3oP

PDB Chain 4r3oP

4r3oQ

PDB Chain 4r3oQ

4r3oR

PDB Chain 4r3oR

4r3oS

PDB Chain 4r3oS

4r3oT

PDB Chain 4r3oT

4r3oU

PDB Chain 4r3oU

4r3oV

PDB Chain 4r3oV

4r3oW

PDB Chain 4r3oW

4r3oX

PDB Chain 4r3oX

4r3oY

PDB Chain 4r3oY

4r3oZ

PDB Chain 4r3oZ

4r3o100

CATH Domain 4r3o100

4r3o200

CATH Domain 4r3o200

4r3oA00

CATH Domain 4r3oA00

4r3oB00

CATH Domain 4r3oB00

4r3oC00

CATH Domain 4r3oC00

4r3oD00

CATH Domain 4r3oD00

4r3oE00

CATH Domain 4r3oE00

4r3oF00

CATH Domain 4r3oF00

4r3oG00

CATH Domain 4r3oG00

4r3oH00

CATH Domain 4r3oH00

4r3oI00

CATH Domain 4r3oI00

4r3oJ00

CATH Domain 4r3oJ00

4r3oK00

CATH Domain 4r3oK00

4r3oL00

CATH Domain 4r3oL00

4r3oM00

CATH Domain 4r3oM00

4r3oN00

CATH Domain 4r3oN00

4r3oO00

CATH Domain 4r3oO00

4r3oP00

CATH Domain 4r3oP00

4r3oQ00

CATH Domain 4r3oQ00

4r3oR00

CATH Domain 4r3oR00

4r3oS00

CATH Domain 4r3oS00

4r3oT00

CATH Domain 4r3oT00

4r3oU00

CATH Domain 4r3oU00

4r3oV00

CATH Domain 4r3oV00

4r3oW00

CATH Domain 4r3oW00

4r3oX00

CATH Domain 4r3oX00

4r3oY00

CATH Domain 4r3oY00

4r3oZ00

CATH Domain 4r3oZ00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
1	29 Jun, 2015	Chopped
2	29 Jun, 2015	Chopped
A	29 Jun, 2015	Chopped
B	29 Jun, 2015	Chopped
C	29 Jun, 2015	Chopped
D	29 Jun, 2015	Chopped
E	29 Jun, 2015	Chopped
F	29 Jun, 2015	Chopped
G	29 Jun, 2015	Chopped
H	29 Jun, 2015	Chopped
I	29 Jun, 2015	Chopped
J	29 Jun, 2015	Chopped
K	29 Jun, 2015	Chopped
L	29 Jun, 2015	Chopped
M	29 Jun, 2015	Chopped
N	29 Jun, 2015	Chopped
O	29 Jun, 2015	Chopped
P	29 Jun, 2015	Chopped
Q	29 Jun, 2015	Chopped
R	29 Jun, 2015	Chopped
S	29 Jun, 2015	Chopped
T	29 Jun, 2015	Chopped
U	29 Jun, 2015	Chopped
V	29 Jun, 2015	Chopped
W	29 Jun, 2015	Chopped
X	29 Jun, 2015	Chopped
Y	29 Jun, 2015	Chopped
Z	29 Jun, 2015	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4r3o100	10 Jul, 2015	3.60.20.10	Assigned
4r3o200	10 Jul, 2015	3.60.20.10	Assigned
4r3oA00	10 Jul, 2015	3.60.20.10	Assigned
4r3oB00	10 Jul, 2015	3.60.20.10	Assigned
4r3oC00	10 Jul, 2015	3.60.20.10	Assigned
4r3oD00	10 Jul, 2015	3.60.20.10	Assigned
4r3oE00	10 Jul, 2015	3.60.20.10	Assigned
4r3oF00	10 Jul, 2015	3.60.20.10	Assigned
4r3oG00	10 Jul, 2015	3.60.20.10	Assigned
4r3oH00	10 Jul, 2015	3.60.20.10	Assigned
4r3oI00	10 Jul, 2015	3.60.20.10	Assigned
4r3oJ00	10 Jul, 2015	3.60.20.10	Assigned
4r3oK00	10 Jul, 2015	3.60.20.10	Assigned
4r3oL00	10 Jul, 2015	3.60.20.10	Assigned
4r3oM00	10 Jul, 2015	3.60.20.10	Assigned
4r3oN00	10 Jul, 2015	3.60.20.10	Assigned
4r3oO00	10 Jul, 2015	3.60.20.10	Assigned
4r3oP00	10 Jul, 2015	3.60.20.10	Assigned
4r3oQ00	10 Jul, 2015	3.60.20.10	Assigned
4r3oR00	10 Jul, 2015	3.60.20.10	Assigned
4r3oS00	10 Jul, 2015	3.60.20.10	Assigned
4r3oT00	10 Jul, 2015	3.60.20.10	Assigned
4r3oU00	10 Jul, 2015	3.60.20.10	Assigned
4r3oV00	10 Jul, 2015	3.60.20.10	Assigned
4r3oW00	10 Jul, 2015	3.60.20.10	Assigned
4r3oX00	10 Jul, 2015	3.60.20.10	Assigned
4r3oY00	10 Jul, 2015	3.60.20.10	Assigned
4r3oZ00	10 Jul, 2015	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P49721	PSB2_HUMAN	Homo sapiens	Proteasome subunit beta type-2
P49720	PSB3_HUMAN	Homo sapiens	Proteasome subunit beta type-3
P28074	PSB5_HUMAN	Homo sapiens	Proteasome subunit beta type-5
P28072	PSB6_HUMAN	Homo sapiens	Proteasome subunit beta type-6
O14818	PSA7_HUMAN	Homo sapiens	Proteasome subunit alpha type-7
P25787	PSA2_HUMAN	Homo sapiens	Proteasome subunit alpha type-2
P25787	PSA2_HUMAN	Homo sapiens	Proteasome subunit alpha type-2
P25786	PSA1_HUMAN	Homo sapiens	Proteasome subunit alpha type-1
O14818	PSA7_HUMAN	Homo sapiens	Proteasome subunit alpha type-7
P25789	PSA4_HUMAN	Homo sapiens	Proteasome subunit alpha type-4
P49720	PSB3_HUMAN	Homo sapiens	Proteasome subunit beta type-3
P20618	PSB1_HUMAN	Homo sapiens	Proteasome subunit beta type-1
P25789	PSA4_HUMAN	Homo sapiens	Proteasome subunit alpha type-4
P60900	PSA6_HUMAN	Homo sapiens	Proteasome subunit alpha type-6
P60900	PSA6_HUMAN	Homo sapiens	Proteasome subunit alpha type-6
P28072	PSB6_HUMAN	Homo sapiens	Proteasome subunit beta type-6
P20618	PSB1_HUMAN	Homo sapiens	Proteasome subunit beta type-1
P25788	PSA3_HUMAN	Homo sapiens	Proteasome subunit alpha type-3
P49721	PSB2_HUMAN	Homo sapiens	Proteasome subunit beta type-2
Q99436	PSB7_HUMAN	Homo sapiens	Proteasome subunit beta type-7
P25786	PSA1_HUMAN	Homo sapiens	Proteasome subunit alpha type-1
P28066	PSA5_HUMAN	Homo sapiens	Proteasome subunit alpha type-5
P25788	PSA3_HUMAN	Homo sapiens	Proteasome subunit alpha type-3
Q99436	PSB7_HUMAN	Homo sapiens	Proteasome subunit beta type-7
P28066	PSA5_HUMAN	Homo sapiens	Proteasome subunit alpha type-5
P28070	PSB4_HUMAN	Homo sapiens	Proteasome subunit beta type-4
P28070	PSB4_HUMAN	Homo sapiens	Proteasome subunit beta type-4
P28074	PSB5_HUMAN	Homo sapiens	Proteasome subunit beta type-5