PDB 4qt1

PDB Information

PDB4QT1
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Scaffold hopping towards potent and selective JAK3 inhibitors: discovery of novel C-5 substituted pyrrolopyrazines
De Vicente, J., Lemoine, R., Bartlett, M., Hermann, J.C., Hekmat-Nejad, M., Henningsen, R., Jin, S., Kuglstatter, A., Li, H., Lovey, A.J., Menke, J., Niu, L., Patel, V., Petersen, A., Setti, L., Shao, A., Tivitmahaisoon, P., Vu, M.D., Soth, M.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2014-07-07
Resolution2.400
CATH Insert Date28 Jun, 2015

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4qt1A01 10 Jul, 2015 3.30.200.20 Assigned
4qt1A02 10 Jul, 2015 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P52333 JAK3_HUMAN Homo sapiens Tyrosine-protein kinase JAK3
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