PDB 4q18

PDB Information

PDB4Q18
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-guided development of deoxycytidine kinase inhibitors with nanomolar affinity and improved metabolic stability.
Nomme, J., Li, Z., Gipson, R.M., Wang, J., Armijo, A.L., Le, T., Poddar, S., Smith, T., Santarsiero, B.D., Nguyen, H.A., Czernin, J., Alexandrova, A.N., Jung, M.E., Radu, C.G., Lavie, A.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2014-04-03
Resolution2.000
CATH Insert Date16 Nov, 2014

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 17 Nov, 2014 Chopped
B 17 Nov, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4q18A00 19 Nov, 2014 3.40.50.300 Assigned
4q18B00 19 Nov, 2014 3.40.50.300 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P27707 DCK_HUMAN Homo sapiens Deoxycytidine kinase
P27707 DCK_HUMAN Homo sapiens Deoxycytidine kinase
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