PDB 4pzx

PDB Information

PDB4PZX
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Synthesis, characterization, and PK/PD studies of a series of spirocyclic pyranochromene BACE1 inhibitors.
Volgraf, M., Chan, L., Huestis, M.P., Purkey, H.E., Burkard, M., Geck Do, M., Harris, J., Hunt, K.W., Liu, X., Lyssikatos, J.P., Rana, S., Thomas, A.A., Vigers, G.P., Siu, M.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2014-03-31
Resolution1.800
CATH Insert Date18 May, 2014

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 19 May, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4pzxA01 21 May, 2014 2.40.70.10 Assigned
4pzxA02 21 May, 2014 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1