PDB 4pzw
PDB Information
PDB | 4PZW |
Method | X-RAY DIFFRACTION |
Host Organism | Escherichia coli |
Gene Source | Homo sapiens |
Primary Citation | Synthesis, characterization, and PK/PD studies of a series of spirocyclic pyranochromene BACE1 inhibitors.
Bioorg.Med.Chem.Lett.
|
Header | Hydrolase/Hydrolase Inhibitor |
Released | 2014-03-31 |
Resolution | 1.800 |
CATH Insert Date | 18 May, 2014 |
PDB Images (4)
PDB Prints
PDB Chains (1)
Chain ID | Date inserted into CATH | CATH Status |
---|---|---|
A | 19 May, 2014 | Chopped |
CATH Domains (2)
Domain ID | Date inserted into CATH | Superfamily | CATH Status |
---|---|---|---|
4pzwA01 | 21 May, 2014 | 2.40.70.10 | Assigned |
4pzwA02 | 21 May, 2014 | 2.40.70.10 | Assigned |
UniProtKB Entries (1)
Accession | Gene ID | Taxon | Description |
---|---|---|---|
P56817 | BACE1_HUMAN | Homo sapiens | Beta-secretase 1 |