PDB Information

PDB4PY1
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Kinase domain inhibition of leucine rich repeat kinase 2 (LRRK2) using a [1,2,4]triazolo[4,3-b]pyridazine scaffold.
Galatsis, P., Henderson, J.L., Kormos, B.L., Han, S., Kurumbail, R.G., Wager, T.T., Verhoest, P.R., Noell, G.S., Chen, Y., Needle, E., Berger, Z., Steyn, S.J., Houle, C., Hirst, W.D.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2014-03-25
Resolution2.160
CATH Insert Date14 Sep, 2014

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 15 Sep, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4py1A01 16 Sep, 2014 3.30.200.20 Assigned
4py1A02 16 Sep, 2014 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P29597 TYK2_HUMAN Homo sapiens Non-receptor tyrosine-protein kinase TYK2
CATH-Gene3D is a Global Biodata Core Resource Learn more...