PDB 4pv0

PDB Information

PDB4PV0
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of GS-9973, a Selective and Orally Efficacious Inhibitor of Spleen Tyrosine Kinase.
Currie, K.S., Kropf, J.E., Lee, T., Blomgren, P., Xu, J., Zhao, Z., Gallion, S., Whitney, J.A., Maclin, D., Lansdon, E.B., Maciejewski, P., Rossi, A.M., Rong, H., Macaluso, J., Barbosa, J., Di Paolo, J.A., Mitchell, S.A.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2014-03-14
Resolution2.000
CATH Insert Date25 May, 2014

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 26 May, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4pv0A01 28 May, 2014 3.30.200.20 Assigned
4pv0A02 28 May, 2014 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P43405 KSYK_HUMAN Homo sapiens Tyrosine-protein kinase SYK
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