PDB 4ptc

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Overview

PDB Information

PDB	4PTC
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core. Sivaprakasam, P., Han, X., Civiello, R.L., Jacutin-Porte, S., Kish, K., Pokross, M., Lewis, H.A., Ahmed, N., Szapiel, N., Newitt, J.A., Baldwin, E.T., Xiao, H., Krause, C.M., Park, H., Nophsker, M., Lippy, J.S., Burton, C.R., Langley, D.R., Macor, J.E., Dubowchik, G.M. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2014-03-10
Resolution	2.710
CATH Insert Date	28 Jun, 2015

PDB Images (7)

Image of CATH 4ptc

4ptc

PDB 4ptc

Image of CATH 4ptcA

4ptcA

PDB Chain 4ptcA

Image of CATH 4ptcB

4ptcB

PDB Chain 4ptcB

Image of CATH 4ptcA01

4ptcA01

CATH Domain 4ptcA01

Image of CATH 4ptcA02

4ptcA02

CATH Domain 4ptcA02

Image of CATH 4ptcB01

4ptcB01

CATH Domain 4ptcB01

Image of CATH 4ptcB02

4ptcB02

CATH Domain 4ptcB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	29 Jun, 2015	Chopped
B	29 Jun, 2015	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4ptcA01	10 Jul, 2015	3.30.200.20	Assigned
4ptcA02	10 Jul, 2015	1.10.510.10	Assigned
4ptcB01	10 Jul, 2015	3.30.200.20	Assigned
4ptcB02	10 Jul, 2015	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P49841	GSK3B_HUMAN	Homo sapiens	Glycogen synthase kinase-3 beta
P49841	GSK3B_HUMAN	Homo sapiens	Glycogen synthase kinase-3 beta