PDB 4pfc

PDB Links
Overview

PDB Information

PDB	4PFC
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Dual Exosite-binding Inhibitors of Insulin-degrading Enzyme Challenge Its Role as the Primary Mediator of Insulin Clearance in Vivo. Durham, T.B., Toth, J.L., Klimkowski, V.J., Cao, J.X., Siesky, A.M., Alexander-Chacko, J., Wu, G.Y., Dixon, J.T., McGee, J.E., Wang, Y., Guo, S.Y., Cavitt, R.N., Schindler, J., Thibodeaux, S.J., Calvert, N.A., Coghlan, M.J., Sindelar, D.K., Christe, M., Kiselyov, V.V., Michael, M.D., Sloop, K.W. J.Biol.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2014-04-28
Resolution	2.210
CATH Insert Date	28 Jun, 2015

PDB Images (11)

Image of CATH 4pfc

4pfc

PDB 4pfc

Image of CATH 4pfcA

4pfcA

PDB Chain 4pfcA

Image of CATH 4pfcB

4pfcB

PDB Chain 4pfcB

Image of CATH 4pfcA01

4pfcA01

CATH Domain 4pfcA01

Image of CATH 4pfcA02

4pfcA02

CATH Domain 4pfcA02

Image of CATH 4pfcA03

4pfcA03

CATH Domain 4pfcA03

Image of CATH 4pfcA04

4pfcA04

CATH Domain 4pfcA04

Image of CATH 4pfcB01

4pfcB01

CATH Domain 4pfcB01

Image of CATH 4pfcB02

4pfcB02

CATH Domain 4pfcB02

Image of CATH 4pfcB03

4pfcB03

CATH Domain 4pfcB03

Image of CATH 4pfcB04

4pfcB04

CATH Domain 4pfcB04

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	29 Jun, 2015	Chopped
B	29 Jun, 2015	Chopped

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4pfcA01	10 Jul, 2015	3.30.830.10	Assigned
4pfcA02	10 Jul, 2015	3.30.830.10	Assigned
4pfcA03	10 Jul, 2015	3.30.830.10	Assigned
4pfcA04	10 Jul, 2015	3.30.830.10	Assigned
4pfcB01	10 Jul, 2015	3.30.830.10	Assigned
4pfcB02	10 Jul, 2015	3.30.830.10	Assigned
4pfcB03	10 Jul, 2015	3.30.830.10	Assigned
4pfcB04	10 Jul, 2015	3.30.830.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P14735	IDE_HUMAN	Homo sapiens	Insulin-degrading enzyme
P14735	IDE_HUMAN	Homo sapiens	Insulin-degrading enzyme