PDB 4pf9

PDB Links
Overview

PDB Information

PDB	4PF9
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Dual Exosite-binding Inhibitors of Insulin-degrading Enzyme Challenge Its Role as the Primary Mediator of Insulin Clearance in Vivo. Durham, T.B., Toth, J.L., Klimkowski, V.J., Cao, J.X., Siesky, A.M., Alexander-Chacko, J., Wu, G.Y., Dixon, J.T., McGee, J.E., Wang, Y., Guo, S.Y., Cavitt, R.N., Schindler, J., Thibodeaux, S.J., Calvert, N.A., Coghlan, M.J., Sindelar, D.K., Christe, M., Kiselyov, V.V., Michael, M.D., Sloop, K.W. J.Biol.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2014-04-28
Resolution	2.500
CATH Insert Date	28 Jun, 2015

PDB Images (11)

Image of CATH 4pf9

4pf9

PDB 4pf9

Image of CATH 4pf9A

4pf9A

PDB Chain 4pf9A

Image of CATH 4pf9B

4pf9B

PDB Chain 4pf9B

Image of CATH 4pf9A01

4pf9A01

CATH Domain 4pf9A01

Image of CATH 4pf9A02

4pf9A02

CATH Domain 4pf9A02

Image of CATH 4pf9A03

4pf9A03

CATH Domain 4pf9A03

Image of CATH 4pf9A04

4pf9A04

CATH Domain 4pf9A04

Image of CATH 4pf9B01

4pf9B01

CATH Domain 4pf9B01

Image of CATH 4pf9B02

4pf9B02

CATH Domain 4pf9B02

Image of CATH 4pf9B03

4pf9B03

CATH Domain 4pf9B03

Image of CATH 4pf9B04

4pf9B04

CATH Domain 4pf9B04

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	29 Jun, 2015	Chopped
B	29 Jun, 2015	Chopped

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4pf9A01	10 Jul, 2015	3.30.830.10	Assigned
4pf9A02	10 Jul, 2015	3.30.830.10	Assigned
4pf9A03	10 Jul, 2015	3.30.830.10	Assigned
4pf9A04	10 Jul, 2015	3.30.830.10	Assigned
4pf9B01	10 Jul, 2015	3.30.830.10	Assigned
4pf9B02	10 Jul, 2015	3.30.830.10	Assigned
4pf9B03	10 Jul, 2015	3.30.830.10	Assigned
4pf9B04	10 Jul, 2015	3.30.830.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P14735	IDE_HUMAN	Homo sapiens	Insulin-degrading enzyme
P14735	IDE_HUMAN	Homo sapiens	Insulin-degrading enzyme