PDB 4ogt

PDB Information

PDB4OGT
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Novel Inhibitors of the MDM2-p53 Interaction Featuring Hydrogen Bond Acceptors as Carboxylic Acid Isosteres.
Gonzalez, A.Z., Li, Z., Beck, H.P., Canon, J., Chen, A., Chow, D., Duquette, J., Eksterowicz, J., Fox, B.M., Fu, J., Huang, X., Houze, J., Jin, L., Li, Y., Ling, Y., Lo, M.C., Long, A.M., McGee, L.R., McIntosh, J., Oliner, J.D., Osgood, T., Rew, Y., Saiki, A.Y., Shaffer, P., Wortman, S., Yakowec, P., Yan, X., Ye, Q., Yu, D., Zhao, X., Zhou, J., Olson, S.H., Sun, D., Medina, J.C.
J.Med.Chem.
HeaderLigase/Ligase Inhibitor
Released2014-01-16
Resolution1.540
CATH Insert Date06 Apr, 2014

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 07 Apr, 2014 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4ogtA01 25 Apr, 2014 1.10.245.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2