PDB Information

PDB4O97
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-guided discovery of 1,3,5 tri-substituted benzenes as potent and selective matriptase inhibitors exhibiting in vivo antitumor efficacy.
Goswami, R., Mukherjee, S., Ghadiyaram, C., Wohlfahrt, G., Sistla, R.K., Nagaraj, J., Satyam, L.K., Subbarao, K., Palakurthy, R.K., Gopinath, S., Krishnamurthy, N.R., Ikonen, T., Moilanen, A., Subramanya, H.S., Kallio, P., Ramachandra, M.
Bioorg.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2014-01-02
Resolution2.200
CATH Insert Date01 Jun, 2014

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 02 Jun, 2014 Chopped
B 02 Jun, 2014 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4o97A01 03 Jun, 2014 2.40.10.10 Assigned
4o97A02 03 Jun, 2014 2.40.10.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9Y5Y6 ST14_HUMAN Homo sapiens Suppressor of tumorigenicity 14 protein
Q9Y5Y6 ST14_HUMAN Homo sapiens Suppressor of tumorigenicity 14 protein
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