PDB Information

PDB4NYJ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchange.
Burns, M.C., Sun, Q., Daniels, R.N., Camper, D., Kennedy, J.P., Phan, J., Olejniczak, E.T., Lee, T., Waterson, A.G., Rossanese, O.W., Fesik, S.W.
Proc.Natl.Acad.Sci.USA
HeaderSignaling Protein
Released2013-12-10
Resolution2.850
CATH Insert Date16 Mar, 2014

PDB Images (8)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
Q 17 Mar, 2014 Chopped
R 17 Mar, 2014 Chopped
S 17 Mar, 2014 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4nyjQ00 25 Apr, 2014 3.40.50.300 Assigned
4nyjR00 25 Apr, 2014 3.40.50.300 Assigned
4nyjS01 17 Apr, 2014 1.20.870.10 Assigned
4nyjS02 17 Apr, 2014 1.10.840.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P01112 RASH_HUMAN Homo sapiens GTPase HRas
Q07889 SOS1_HUMAN Homo sapiens Son of sevenless homolog 1
P01112 RASH_HUMAN Homo sapiens GTPase HRas
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