PDB 4nxs

PDB Links
Overview

PDB Information

PDB	4NXS
Method	X-RAY DIFFRACTION
Host Organism	Cricetulus griseus
Gene Source	Homo sapiens
Primary Citation	Molecular Basis of 1-Deoxygalactonojirimycin Arylthiourea Binding to Human alpha-Galactosidase A: Pharmacological Chaperoning Efficacy on Fabry Disease Mutants. Yu, Y., Mena-Barragan, T., Higaki, K., Johnson, J.L., Drury, J.E., Lieberman, R.L., Nakasone, N., Ninomiya, H., Tsukimura, T., Sakuraba, H., Suzuki, Y., Nanba, E., Mellet, C.O., Garcia Fernandez, J.M., Ohno, K. Acs Chem.Biol.
Header	Hydrolase/Hydrolase Inhibitor
Released	2013-12-09
Resolution	2.550
CATH Insert Date	29 Jun, 2014

PDB Images (7)

Image of CATH 4nxs

4nxs

PDB 4nxs

Image of CATH 4nxsA

4nxsA

PDB Chain 4nxsA

Image of CATH 4nxsB

4nxsB

PDB Chain 4nxsB

Image of CATH 4nxsA01

4nxsA01

CATH Domain 4nxsA01

Image of CATH 4nxsA02

4nxsA02

CATH Domain 4nxsA02

Image of CATH 4nxsB01

4nxsB01

CATH Domain 4nxsB01

Image of CATH 4nxsB02

4nxsB02

CATH Domain 4nxsB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	30 Jun, 2014	Chopped
B	30 Jun, 2014	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4nxsA01	03 Jul, 2014	3.20.20.70	Assigned
4nxsA02	03 Jul, 2014	2.60.40.1180	Assigned
4nxsB01	02 Jul, 2014	3.20.20.70	Assigned
4nxsB02	02 Jul, 2014	2.60.40.1180	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P06280	AGAL_HUMAN	Homo sapiens	Alpha-galactosidase A
P06280	AGAL_HUMAN	Homo sapiens	Alpha-galactosidase A