PDB Information

PDB4NMM
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
In situ selectivity profiling and crystal structure of SML-8-73-1, an active site inhibitor of oncogenic K-Ras G12C.
Hunter, J.C., Gurbani, D., Ficarro, S.B., Carrasco, M.A., Lim, S.M., Choi, H.G., Xie, T., Marto, J.A., Chen, Z., Gray, N.S., Westover, K.D.
Proc.Natl.Acad.Sci.USA
HeaderHydrolase/Hydrolase Inhibitor
Released2013-11-15
Resolution1.890
CATH Insert Date15 Jun, 2014

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Jun, 2014 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4nmmA00 18 Jun, 2014 3.40.50.300 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P01116 RASK_HUMAN Homo sapiens GTPase KRas