PDB Information

PDB4NH7
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Correlation between chemotype-dependent binding conformations of HSP90 alpha / beta and isoform selectivity-Implications for the structure-based design of HSP90 alpha / beta selective inhibitors for treating neurodegenerative diseases.
Ernst, J.T., Liu, M., Zuccola, H., Neubert, T., Beaumont, K., Turnbull, A., Kallel, A., Vought, B., Stamos, D.
Bioorg.Med.Chem.Lett.
HeaderChaperone
Released2013-11-04
Resolution2.000
CATH Insert Date02 Feb, 2014

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 03 Feb, 2014 Chopped
B 03 Feb, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4nh7A00 07 Mar, 2014 3.30.565.10 Assigned
4nh7B00 07 Mar, 2014 3.30.565.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P07900 HS90A_HUMAN Homo sapiens Heat shock protein HSP 90-alpha
P07900 HS90A_HUMAN Homo sapiens Heat shock protein HSP 90-alpha