PDB Information

PDB4NA8
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Tetrahydroquinoline Derivatives as Potent and Selective Factor XIa Inhibitors.
Quan, M.L., Wong, P.C., Wang, C., Woerner, F., Smallheer, J.M., Barbera, F.A., Bozarth, J.M., Brown, R.L., Harpel, M.R., Luettgen, J.M., Morin, P.E., Peterson, T., Ramamurthy, V., Rendina, A.R., Rossi, K.A., Watson, C.A., Wei, A., Zhang, G., Seiffert, D., Wexler, R.R.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2013-10-21
Resolution2.300
CATH Insert Date16 Feb, 2014

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 17 Feb, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4na8A01 07 Mar, 2014 2.40.10.10 Assigned
4na8A02 07 Mar, 2014 2.40.10.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P03951 FA11_HUMAN Homo sapiens Coagulation factor XI
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