PDB 4msc

PDB Links
Overview

PDB Information

PDB	4MSC
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Identification and optimization of PDE10A inhibitors using fragment-based screening by nanocalorimetry and X-ray crystallography. Recht, M.I., Sridhar, V., Badger, J., Bounaud, P.Y., Logan, C., Chie-Leon, B., Nienaber, V., Torres, F.E. J Biomol Screen
Header	Hydrolase/Hydrolase Inhibitor
Released	2013-09-18
Resolution	2.470
CATH Insert Date	18 May, 2014

PDB Images (5)

Image of CATH 4msc

4msc

PDB 4msc

Image of CATH 4mscA

4mscA

PDB Chain 4mscA

Image of CATH 4mscB

4mscB

PDB Chain 4mscB

Image of CATH 4mscA00

4mscA00

CATH Domain 4mscA00

Image of CATH 4mscB00

4mscB00

CATH Domain 4mscB00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	19 May, 2014	Chopped
B	19 May, 2014	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4mscA00	21 May, 2014	1.10.1300.10	Assigned
4mscB00	21 May, 2014	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A