PDB 4mr5

PDB Information

PDB4MR5
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain.
Picaud, S., Wells, C., Felletar, I., Brotherton, D., Martin, S., Savitsky, P., Diez-Dacal, B., Philpott, M., Bountra, C., Lingard, H., Fedorov, O., Muller, S., Brennan, P.E., Knapp, S., Filippakopoulos, P.
Proc.Natl.Acad.Sci.USA
HeaderTranscription/Transcription Inhibitor
Released2013-09-17
Resolution1.630
CATH Insert Date01 Dec, 2013

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 02 Dec, 2013 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4mr5A00 04 Dec, 2013 1.20.920.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P25440 BRD2_HUMAN Homo sapiens Bromodomain-containing protein 2
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