PDB 4mq2

PDB Information

PDB4MQ2
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Pyrido[2,3-d]pyrimidines: Discovery and preliminary SAR of a novel series of DYRK1B and DYRK1A inhibitors.
Anderson, K., Chen, Y., Chen, Z., Dominique, R., Glenn, K., He, Y., Janson, C., Luk, K.C., Lukacs, C., Polonskaia, A., Qiao, Q., Railkar, A., Rossman, P., Sun, H., Xiang, Q., Vilenchik, M., Wovkulich, P., Zhang, X.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2013-09-15
Resolution2.800
CATH Insert Date15 Dec, 2013

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2013 Chopped
B 16 Dec, 2013 Chopped
C 16 Dec, 2013 Chopped
D 16 Dec, 2013 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4mq2A01 20 Dec, 2013 3.30.200.20 Assigned
4mq2A02 20 Dec, 2013 1.10.510.10 Assigned
4mq2B01 20 Dec, 2013 3.30.200.20 Assigned
4mq2B02 20 Dec, 2013 1.10.510.10 Assigned
4mq2C01 20 Dec, 2013 3.30.200.20 Assigned
4mq2C02 20 Dec, 2013 1.10.510.10 Assigned
4mq2D01 20 Dec, 2013 3.30.200.20 Assigned
4mq2D02 20 Dec, 2013 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q13627 DYR1A_HUMAN Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1A
Q13627 DYR1A_HUMAN Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1A
Q13627 DYR1A_HUMAN Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1A
Q13627 DYR1A_HUMAN Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1A