PDB Information

PDB4MPE
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-guided Development of Specific Pyruvate Dehydrogenase Kinase Inhibitors Targeting the ATP-binding Pocket.
Tso, S.C., Qi, X., Gui, W.J., Wu, C.Y., Chuang, J.L., Wernstedt-Asterholm, I., Morlock, L.K., Owens, K.R., Scherer, P.E., Williams, N.S., Tambar, U.K., Wynn, R.M., Chuang, D.T.
J.Biol.Chem.
HeaderTransferase/Transferase Inhibitor
Released2013-09-12
Resolution1.950
CATH Insert Date05 Jan, 2014

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 06 Jan, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4mpeA01 09 Jan, 2014 1.20.140.20 Assigned
4mpeA02 09 Jan, 2014 3.30.565.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q15119 PDK2_HUMAN Homo sapiens [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial
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