PDB Information

PDB4MD6
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of 3-(4-hydroxybenzyl)-1-(thiophen-2-yl)chromeno[2,3-c]pyrrol-9(2H)-one as a phosphodiesterase-5 inhibitor and its complex crystal structure.
Shang, N.N., Shao, Y.X., Cai, Y.H., Guan, M., Huang, M., Cui, W., He, L., Yu, Y.J., Huang, L., Li, Z., Bu, X.Z., Ke, H., Luo, H.B.
Biochem Pharmacol
HeaderHydrolase/Hydrolase Inhibitor
Released2013-08-22
Resolution2.000
CATH Insert Date20 Jul, 2014

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 21 Jul, 2014 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4md6A00 27 Jul, 2014 1.10.1300.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O76074 PDE5A_HUMAN Homo sapiens cGMP-specific 3',5'-cyclic phosphodiesterase
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