PDB 4m12

PDB Information

PDB4M12
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors.
Han, S., Czerwinski, R.M., Caspers, N.L., Limburg, D.C., Ding, W., Wang, H., Ohren, J.F., Rajamohan, F., McLellan, T.J., Unwalla, R., Choi, C., Parikh, M.D., Seth, N., Edmonds, J., Phillips, C., Shakya, S., Li, X., Spaulding, V., Hughes, S., Cook, A., Robinson, C., Mathias, J.P., Navratilova, I., Medley, Q.G., Anderson, D.R., Kurumbail, R.G., Aulabaugh, A.
Biochem.J.
HeaderTransferase/Transferase Inhibitor
Released2013-08-02
Resolution2.150
CATH Insert Date06 Apr, 2014

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 07 Apr, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4m12A01 25 Apr, 2014 3.30.200.20 Assigned
4m12A02 25 Apr, 2014 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q08881 ITK_HUMAN Homo sapiens Tyrosine-protein kinase ITK/TSK
CATH-Gene3D is a Global Biodata Core Resource Learn more...