PDB 4lxb
PDB Information
PDB | 4LXB |
Method | X-RAY DIFFRACTION |
Host Organism | |
Gene Source | |
Primary Citation | 5-Chlorothiophene-2-carboxylic acid [(S)-2-[2-methyl-3-(2-oxopyrrolidin-1-yl)benzenesulfonylamino]-3-(4-methylpiperazin-1-yl)-3-oxopropyl]amide (SAR107375), a selective and potent orally active dual thrombin and factor Xa inhibitor.
J.Med.Chem.
|
Header | Hydrolase/Hydrolase Inhibitor |
Released | 2013-07-29 |
Resolution | 1.610 |
CATH Insert Date | 29 Jun, 2014 |
PDB Images (6)
PDB Prints
PDB Chains (3)
Chain ID | Date inserted into CATH | CATH Status |
---|---|---|
H | 30 Jun, 2014 | Chopped |
I | 30 Jun, 2014 | Rejected |
L | 30 Jun, 2014 | Rejected |
CATH Domains (2)
Domain ID | Date inserted into CATH | Superfamily | CATH Status |
---|---|---|---|
4lxbH01 | 02 Jul, 2014 | 2.40.10.10 | Assigned |
4lxbH02 | 02 Jul, 2014 | 2.40.10.10 | Assigned |
UniProtKB Entries (3)
Accession | Gene ID | Taxon | Description |
---|---|---|---|
P00734 | THRB_HUMAN | Homo sapiens | Prothrombin |
P00734 | THRB_HUMAN | Homo sapiens | Prothrombin |
P01050 | HIRV1_HIRME | Hirudo medicinalis | Hirudin variant-1 |