PDB 4loy
PDB Information
PDB | 4LOY |
Method | X-RAY DIFFRACTION |
Host Organism | |
Gene Source | |
Primary Citation | 5-Chlorothiophene-2-carboxylic acid [(S)-2-[2-methyl-3-(2-oxopyrrolidin-1-yl)benzenesulfonylamino]-3-(4-methylpiperazin-1-yl)-3-oxopropyl]amide (SAR107375), a selective and potent orally active dual thrombin and factor Xa inhibitor.
J.Med.Chem.
|
Header | Hydrolase/Hydrolase Inhibitor |
Released | 2013-07-14 |
Resolution | 1.770 |
CATH Insert Date | 15 Jun, 2014 |
PDB Images (6)
PDB Prints
PDB Chains (3)
Chain ID | Date inserted into CATH | CATH Status |
---|---|---|
H | 16 Jun, 2014 | Chopped |
I | 16 Jun, 2014 | Rejected |
L | 16 Jun, 2014 | Rejected |
CATH Domains (2)
Domain ID | Date inserted into CATH | Superfamily | CATH Status |
---|---|---|---|
4loyH01 | 18 Jun, 2014 | 2.40.10.10 | Assigned |
4loyH02 | 18 Jun, 2014 | 2.40.10.10 | Assigned |
UniProtKB Entries (3)
Accession | Gene ID | Taxon | Description |
---|---|---|---|
P09945 | HIRV2_HIRME | Hirudo medicinalis | Hirudin variant-2 |
P00734 | THRB_HUMAN | Homo sapiens | Prothrombin |
P00734 | THRB_HUMAN | Homo sapiens | Prothrombin |