PDB 4l52

PDB Links
Overview

PDB Information

PDB	4L52
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Discovery and optimization of 7-aminofuro[2,3-c]pyridine inhibitors of TAK1. Hornberger, K.R., Berger, D.M., Crew, A.P., Dong, H., Kleinberg, A., Li, A.H., Medeiros, M.R., Mulvihill, M.J., Siu, K., Tarrant, J., Wang, J., Weng, F., Wilde, V.L., Albertella, M., Bittner, M., Cooke, A., Gray, M.J., Maresca, P., May, E., Meyn, P., Peick, W., Romashko, D., Tanowitz, M., Tokar, B. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2013-06-10
Resolution	2.540
CATH Insert Date	04 Aug, 2013

PDB Images (4)

Image of CATH 4l52

4l52

PDB 4l52

Image of CATH 4l52A

4l52A

PDB Chain 4l52A

Image of CATH 4l52A01

4l52A01

CATH Domain 4l52A01

Image of CATH 4l52A02

4l52A02

CATH Domain 4l52A02

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	05 Aug, 2013	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4l52A01	14 Aug, 2013	3.30.200.20	Assigned
4l52A02	14 Aug, 2013	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q15750	TAB1_HUMAN	Homo sapiens	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
O43318	M3K7_HUMAN	Homo sapiens	Mitogen-activated protein kinase kinase kinase 7