PDB 4l3p

PDB Links
Overview

PDB Information

PDB	4L3P
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Discovery and optimization of 7-aminofuro[2,3-c]pyridine inhibitors of TAK1. Hornberger, K.R., Berger, D.M., Crew, A.P., Dong, H., Kleinberg, A., Li, A.H., Medeiros, M.R., Mulvihill, M.J., Siu, K., Tarrant, J., Wang, J., Weng, F., Wilde, V.L., Albertella, M., Bittner, M., Cooke, A., Gray, M.J., Maresca, P., May, E., Meyn, P., Peick, W., Romashko, D., Tanowitz, M., Tokar, B. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2013-06-06
Resolution	2.680
CATH Insert Date	07 Jul, 2013

PDB Images (4)

Image of CATH 4l3p

4l3p

PDB 4l3p

Image of CATH 4l3pA

4l3pA

PDB Chain 4l3pA

Image of CATH 4l3pA01

4l3pA01

CATH Domain 4l3pA01

Image of CATH 4l3pA02

4l3pA02

CATH Domain 4l3pA02

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	08 Jul, 2013	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4l3pA01	09 Aug, 2013	3.30.200.20	Assigned
4l3pA02	09 Aug, 2013	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q15750	TAB1_HUMAN	Homo sapiens	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
O43318	M3K7_HUMAN	Homo sapiens	Mitogen-activated protein kinase kinase kinase 7