PDB 4l2y

PDB Links
Overview

PDB Information

PDB	4L2Y
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Crystal Structures of PI3K alpha Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design. Zhao, Y., Zhang, X., Chen, Y., Lu, S., Peng, Y., Wang, X., Guo, C., Zhou, A., Zhang, J., Luo, Y., Shen, Q., Ding, J., Meng, L., Zhang, J. ACS Med Chem Lett
Header	Signaling Protein/Transferase/Inhibitor
Released	2013-06-05
Resolution	2.800
CATH Insert Date	05 Jan, 2014

PDB Images (10)

Image of CATH 4l2y

4l2y

PDB 4l2y

Image of CATH 4l2yA

4l2yA

PDB Chain 4l2yA

Image of CATH 4l2yB

4l2yB

PDB Chain 4l2yB

Image of CATH 4l2yA01

4l2yA01

CATH Domain 4l2yA01

Image of CATH 4l2yA02

4l2yA02

CATH Domain 4l2yA02

Image of CATH 4l2yA03

4l2yA03

CATH Domain 4l2yA03

Image of CATH 4l2yA04

4l2yA04

CATH Domain 4l2yA04

Image of CATH 4l2yA05

4l2yA05

CATH Domain 4l2yA05

Image of CATH 4l2yB01

4l2yB01

CATH Domain 4l2yB01

Image of CATH 4l2yB02

4l2yB02

CATH Domain 4l2yB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	06 Jan, 2014	Chopped
B	06 Jan, 2014	Chopped

CATH Domains (7)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4l2yA01	09 Jan, 2014	3.10.20.770	Assigned
4l2yA02	09 Jan, 2014	2.60.40.150	Assigned
4l2yA03	09 Jan, 2014	1.25.40.70	Assigned
4l2yA04	09 Jan, 2014	3.30.1010.10	Assigned
4l2yA05	09 Jan, 2014	1.10.1070.11	Assigned
4l2yB01	14 Nov, 2017		Holding pen
4l2yB02	14 Nov, 2017	1.10.287.1490	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P27986	P85A_HUMAN	Homo sapiens	Phosphatidylinositol 3-kinase regulatory subunit alpha
P42336	PK3CA_HUMAN	Homo sapiens	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform