PDB 4l23
PDB Information
PDB | 4L23 |
Method | X-RAY DIFFRACTION |
Host Organism | Spodoptera frugiperda |
Gene Source | Homo sapiens |
Primary Citation | Crystal Structures of PI3K alpha Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design.
ACS Med Chem Lett
|
Header | Signaling Protein/Transferase/Inhibitor |
Released | 2013-06-04 |
Resolution | 2.500 |
CATH Insert Date | 05 Jan, 2014 |
PDB Images (10)
PDB Prints
PDB Chains (2)
Chain ID | Date inserted into CATH | CATH Status |
---|---|---|
A | 06 Jan, 2014 | Chopped |
B | 06 Jan, 2014 | Chopped |
CATH Domains (7)
Domain ID | Date inserted into CATH | Superfamily | CATH Status |
---|---|---|---|
4l23A01 | 09 Jan, 2014 | 3.10.20.770 | Assigned |
4l23A02 | 09 Jan, 2014 | 2.60.40.150 | Assigned |
4l23A03 | 09 Jan, 2014 | 1.25.40.70 | Assigned |
4l23A04 | 09 Jan, 2014 | 3.30.1010.10 | Assigned |
4l23A05 | 09 Jan, 2014 | 1.10.1070.11 | Assigned |
4l23B01 | 14 Nov, 2017 | Holding pen | |
4l23B02 | 14 Nov, 2017 | 1.10.287.1490 | Assigned |
UniProtKB Entries (2)
Accession | Gene ID | Taxon | Description |
---|---|---|---|
P27986 | P85A_HUMAN | Homo sapiens | Phosphatidylinositol 3-kinase regulatory subunit alpha |
P42336 | PK3CA_HUMAN | Homo sapiens | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform |