PDB 4l23

PDB Links
Overview

PDB Information

PDB	4L23
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Crystal Structures of PI3K alpha Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design. Zhao, Y., Zhang, X., Chen, Y., Lu, S., Peng, Y., Wang, X., Guo, C., Zhou, A., Zhang, J., Luo, Y., Shen, Q., Ding, J., Meng, L., Zhang, J. ACS Med Chem Lett
Header	Signaling Protein/Transferase/Inhibitor
Released	2013-06-04
Resolution	2.500
CATH Insert Date	05 Jan, 2014

PDB Images (10)

Image of CATH 4l23

4l23

PDB 4l23

Image of CATH 4l23A

4l23A

PDB Chain 4l23A

Image of CATH 4l23B

4l23B

PDB Chain 4l23B

Image of CATH 4l23A01

4l23A01

CATH Domain 4l23A01

Image of CATH 4l23A02

4l23A02

CATH Domain 4l23A02

Image of CATH 4l23A03

4l23A03

CATH Domain 4l23A03

Image of CATH 4l23A04

4l23A04

CATH Domain 4l23A04

Image of CATH 4l23A05

4l23A05

CATH Domain 4l23A05

Image of CATH 4l23B01

4l23B01

CATH Domain 4l23B01

Image of CATH 4l23B02

4l23B02

CATH Domain 4l23B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	06 Jan, 2014	Chopped
B	06 Jan, 2014	Chopped

CATH Domains (7)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4l23A01	09 Jan, 2014	3.10.20.770	Assigned
4l23A02	09 Jan, 2014	2.60.40.150	Assigned
4l23A03	09 Jan, 2014	1.25.40.70	Assigned
4l23A04	09 Jan, 2014	3.30.1010.10	Assigned
4l23A05	09 Jan, 2014	1.10.1070.11	Assigned
4l23B01	14 Nov, 2017		Holding pen
4l23B02	14 Nov, 2017	1.10.287.1490	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P27986	P85A_HUMAN	Homo sapiens	Phosphatidylinositol 3-kinase regulatory subunit alpha
P42336	PK3CA_HUMAN	Homo sapiens	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform