PDB Information

PDB4KZC
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Structure guided optimization of a fragment hit to imidazopyridine inhibitors of PI3K.
Pecchi, S., Ni, Z.J., Han, W., Smith, A., Lan, J., Burger, M., Merritt, H., Wiesmann, M., Chan, J., Kaufman, S., Knapp, M.S., Janssen, J., Huh, K., Voliva, C.F.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2013-05-29
Resolution3.250
CATH Insert Date04 Aug, 2013

PDB Images (7)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Aug, 2013 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
4kzcA01 14 Aug, 2013 3.10.20.90 Assigned
4kzcA02 14 Aug, 2013 2.60.40.150 Assigned
4kzcA03 14 Aug, 2013 1.25.40.70 Assigned
4kzcA04 14 Aug, 2013 3.30.1010.10 Assigned
4kzcA05 14 Aug, 2013 1.10.1070.11 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P48736 PK3CG_HUMAN Homo sapiens Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
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