PDB 4kwf

PDB Information

PDB4KWF
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Development of selective inhibitors for aldehyde dehydrogenases based on substituted indole-2,3-diones.
Kimble-Hill, A.C., Parajuli, B., Chen, C.H., Mochly-Rosen, D., Hurley, T.D.
J.Med.Chem.
HeaderOxidoreductase/Inhibitor
Released2013-05-24
Resolution2.310
CATH Insert Date13 Apr, 2014

PDB Images (25)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 14 Apr, 2014 Chopped
B 14 Apr, 2014 Chopped
C 14 Apr, 2014 Chopped
D 14 Apr, 2014 Chopped
E 14 Apr, 2014 Chopped
F 14 Apr, 2014 Chopped
G 14 Apr, 2014 Chopped
H 14 Apr, 2014 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
4kwfA01 25 Apr, 2014 3.40.605.10 Assigned
4kwfA02 25 Apr, 2014 3.40.309.10 Assigned
4kwfB01 25 Apr, 2014 3.40.605.10 Assigned
4kwfB02 25 Apr, 2014 3.40.309.10 Assigned
4kwfC01 25 Apr, 2014 3.40.605.10 Assigned
4kwfC02 25 Apr, 2014 3.40.309.10 Assigned
4kwfD01 25 Apr, 2014 3.40.605.10 Assigned
4kwfD02 25 Apr, 2014 3.40.309.10 Assigned
4kwfE01 25 Apr, 2014 3.40.605.10 Assigned
4kwfE02 25 Apr, 2014 3.40.309.10 Assigned
4kwfF01 25 Apr, 2014 3.40.605.10 Assigned
4kwfF02 25 Apr, 2014 3.40.309.10 Assigned
4kwfG01 25 Apr, 2014 3.40.605.10 Assigned
4kwfG02 25 Apr, 2014 3.40.309.10 Assigned
4kwfH01 25 Apr, 2014 3.40.605.10 Assigned
4kwfH02 25 Apr, 2014 3.40.309.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
P05091 ALDH2_HUMAN Homo sapiens Aldehyde dehydrogenase, mitochondrial
P05091 ALDH2_HUMAN Homo sapiens Aldehyde dehydrogenase, mitochondrial
P05091 ALDH2_HUMAN Homo sapiens Aldehyde dehydrogenase, mitochondrial
P05091 ALDH2_HUMAN Homo sapiens Aldehyde dehydrogenase, mitochondrial
P05091 ALDH2_HUMAN Homo sapiens Aldehyde dehydrogenase, mitochondrial
P05091 ALDH2_HUMAN Homo sapiens Aldehyde dehydrogenase, mitochondrial
P05091 ALDH2_HUMAN Homo sapiens Aldehyde dehydrogenase, mitochondrial
P05091 ALDH2_HUMAN Homo sapiens Aldehyde dehydrogenase, mitochondrial