PDB 4kju

PDB Information

PDB4KJU
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Optimization of Benzodiazepinones as Selective Inhibitors of the X-Linked Inhibitor of Apoptosis Protein (XIAP) Second Baculovirus IAP Repeat (BIR2) Domain.
Kester, R.F., Donnell, A.F., Lou, Y., Remiszewski, S.W., Lombardo, L.J., Chen, S., Le, N.T., Lo, J., Moliterni, J.A., Han, X., Hogg, J.H., Liang, W., Michoud, C., Rupert, K.C., Mischke, S., Le, K., Weisel, M., Janson, C.A., Lukacs, C.M., Fretland, A.J., Hong, K., Polonskaia, A., Gao, L., Li, S., Solis, D.S., Aguilar, D., Tardell, C., Dvorozniak, M., Tannu, S., Lee, E.C., Schutt, A.D., Goggin, B.
J.Med.Chem.
HeaderApoptosis/Apoptosis Inhibitor
Released2013-05-03
Resolution1.600
CATH Insert Date01 Dec, 2013

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 02 Dec, 2013 Chopped
C 02 Dec, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4kjuA00 04 Dec, 2013 1.10.1170.10 Assigned
4kjuC00 04 Dec, 2013 1.10.1170.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P98170 XIAP_HUMAN Homo sapiens E3 ubiquitin-protein ligase XIAP
P98170 XIAP_HUMAN Homo sapiens E3 ubiquitin-protein ligase XIAP