PDB 4k3j

PDB Links
Overview

PDB Information

PDB	4K3J
Method	X-RAY DIFFRACTION
Host Organism	Trichoplusia ni
Gene Source	Homo sapiens
Primary Citation	Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent. Merchant, M., Ma, X., Maun, H.R., Zheng, Z., Peng, J., Romero, M., Huang, A., Yang, N.Y., Nishimura, M., Greve, J., Santell, L., Zhang, Y.W., Su, Y., Kaufman, D.W., Billeci, K.L., Mai, E., Moffat, B., Lim, A., Duenas, E.T., Phillips, H.S., Xiang, H., Young, J.C., Vande Woude, G.F., Dennis, M.S., Reilly, D.E., Schwall, R.H., Starovasnik, M.A., Lazarus, R.A., Yansura, D.G. Proc.Natl.Acad.Sci.USA
Header	Transferase/Immune System/Growth Factor
Released	2013-04-10
Resolution	2.800
CATH Insert Date	15 Sep, 2013

PDB Images (13)

Image of CATH 4k3j

4k3j

PDB 4k3j

Image of CATH 4k3jA

4k3jA

PDB Chain 4k3jA

Image of CATH 4k3jB

4k3jB

PDB Chain 4k3jB

Image of CATH 4k3jH

4k3jH

PDB Chain 4k3jH

Image of CATH 4k3jL

4k3jL

PDB Chain 4k3jL

Image of CATH 4k3jA01

4k3jA01

CATH Domain 4k3jA01

Image of CATH 4k3jA02

4k3jA02

CATH Domain 4k3jA02

Image of CATH 4k3jB01

4k3jB01

CATH Domain 4k3jB01

Image of CATH 4k3jB02

4k3jB02

CATH Domain 4k3jB02

Image of CATH 4k3jH01

4k3jH01

CATH Domain 4k3jH01

Image of CATH 4k3jH02

4k3jH02

CATH Domain 4k3jH02

Image of CATH 4k3jL01

4k3jL01

CATH Domain 4k3jL01

Image of CATH 4k3jL02

4k3jL02

CATH Domain 4k3jL02

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	16 Sep, 2013	Chopped
B	16 Sep, 2013	Chopped
H	16 Sep, 2013	Chopped
L	16 Sep, 2013	Chopped

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4k3jA01	18 Sep, 2013	2.40.10.10	Assigned
4k3jA02	18 Sep, 2013	2.40.10.10	Assigned
4k3jB01	18 Sep, 2013	2.130.10.10	Assigned
4k3jB02	18 Sep, 2013	3.30.1680.10	Assigned
4k3jH01	18 Sep, 2013	2.60.40.10	Assigned
4k3jH02	18 Sep, 2013	2.60.40.10	Assigned
4k3jL01	18 Sep, 2013	2.60.40.10	Assigned
4k3jL02	18 Sep, 2013	2.60.40.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P08581	MET_HUMAN	Homo sapiens	Hepatocyte growth factor receptor
P14210	HGF_HUMAN	Homo sapiens	Hepatocyte growth factor