PDB 4k18

PDB Information

PDB4K18
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of novel pyrazolo[1,5-a]pyrimidines as potent pan-Pim inhibitors by structure- and property-based drug design.
Wang, X., Magnuson, S., Pastor, R., Fan, E., Hu, H., Tsui, V., Deng, W., Murray, J., Steffek, M., Wallweber, H., Moffat, J., Drummond, J., Chan, G., Harstad, E., Ebens, A.J.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2013-04-04
Resolution2.050
CATH Insert Date07 Jul, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4k18A01 09 Aug, 2013 3.30.200.20 Assigned
4k18A02 09 Aug, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P11309 PIM1_HUMAN Homo sapiens Serine/threonine-protein kinase pim-1
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