PDB Information

PDB4JZR
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Novel complex crystal structure of prolyl hydroxylase domain-containing protein 2 (PHD2): 2,8-Diazaspiro[4.5]decan-1-ones as potent, orally bioavailable PHD2 inhibitors
Deng, G., Zhao, B., Ma, Y., Xu, Q., Wang, H., Yang, L., Zhang, Q., Guo, T.B., Zhang, W., Jiao, Y., Cai, X., Zhang, J., Liu, H., Guan, X., Lu, H., Xiang, J., Elliott, J.D., Lin, X., Ren, F.
Bioorg.Med.Chem.
HeaderOxidoreductase
Released2013-04-03
Resolution2.100
CATH Insert Date03 Nov, 2013

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 04 Nov, 2013 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4jzrA00 06 Nov, 2013 2.60.120.620 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9GZT9 EGLN1_HUMAN Homo sapiens Egl nine homolog 1
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