PDB Information

PDB4JVR
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Rational Design and Binding Mode Duality of MDM2-p53 Inhibitors.
Gonzalez-Lopez de Turiso, F., Sun, D., Rew, Y., Bartberger, M.D., Beck, H.P., Canon, J., Chen, A., Chow, D., Correll, T.L., Huang, X., Julian, L.D., Kayser, F., Lo, M.C., Long, A.M., McMinn, D., Oliner, J.D., Osgood, T., Powers, J.P., Saiki, A.Y., Schneider, S., Shaffer, P., Xiao, S.H., Yakowec, P., Yan, X., Ye, Q., Yu, D., Zhao, X., Zhou, J., Medina, J.C., Olson, S.H.
J.Med.Chem.
HeaderLigase/Ligase Inhibitor
Released2013-03-26
Resolution1.700
CATH Insert Date07 Jul, 2013

PDB Images (7)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped
C 08 Jul, 2013 Chopped
E 08 Jul, 2013 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4jvrA00 09 Aug, 2013 1.10.245.10 Assigned
4jvrC00 09 Aug, 2013 1.10.245.10 Assigned
4jvrE00 09 Aug, 2013 1.10.245.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2